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. 2017 Mar 29;12:593–602. doi: 10.2147/CIA.S132277

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© 2017 Liu et al. This work is published and licensed by Dove Medical Press Limited

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Renal function in septic rats of the three groups.

Notes: (A) Serum Cr concentration. (B) BUN concentration. (C) Severity of AKI 12 h post-CLP. (D) Severity of AKI 24 h post-CLP. AKI was measured based on RIFLE categories. R, I, F = AKI RIFLE classes risk (creatinine change, 150%–199%), injury (creatinine change, 200%–299%), and failure (creatinine change, ≥300%). Data are shown as the mean ± standard error. ^*P<0.05 compared with the control group. ^#P<0.05 compared with the L d-gal group.

Abbreviations: CLP, cecal ligation and puncture; d-gal, d-galactose; H d-gal, high-dose d-gal; L d-gal, low-dose d-gal; Cr, creatinine; BUN, blood urea nitrogen; AKI, acute kidney injury.