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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Curr Opin HIV AIDS. 2016 Sep;11(5):455–464. doi: 10.1097/COH.0000000000000303

Figure 2.

Figure 2

Estimated mortality from enrolment into HIV care in children aged 5–10 years at enrolment with initial CD4 >500 cells/μl from Southern Africa, West Africa and Europe comparing different cART initiation strategies as follows: immediate cART; cART at CD4 < 500 or weight-for-age z-score (WAZ)<−2; CD4 <350/WAZ <−2; CD4 <200/WAZ <−2; no cART. The mortality difference between immediate cART (solid green line) and deferring cART to CD4 >500 cells/μl or WAZ<−2 is 0.4% (95%CI: 0.02–0.6%). Mortality is estimated from g-computation to adjust for time-dependent confounding affected by prior treatment of CD4 count, CD4 percent and weight-for-age z-score.