Table 1.
Serial number | Treatment | % viability |
---|---|---|
1 | DMSO media control | 100.0±1.914* |
2 | DOX control, 1 µM | 49.63±1.44 |
3 | DOX, 1 µM + RUT 50 µM | 64.89±0.948* |
4 | DOX, 1 µM + RUT 100 µM | 73.93±0.841* |
Notes: Data represent mean ± SEM of three tests in triplicates for protective effect of RUT on cell viability against DOX-induced neurotoxicity in MTT assay on IMR32 cells,
P<0.001 compared to DOX control.
Abbreviations: DMSO, dimethyl sulfoxide; DOX, doxorubicin; MTT, 3-[4,5 dimethyl thiazol-2-yl]-2,5-diphenyl tetrazolium bromide; RUT, rutin; SEM, standard error of the mean.