Table 3.
Hematological profiling
| Parameters | Treatment group
|
|||
|---|---|---|---|---|
| Vehicle control | DOX control | RUT + DOX | RUT | |
| RBC (×106 cells/µL) | 8.04±0.146 | 5.89±0.219* | 9.07±0.42# | 9.28±0.124# |
| Hb % (g/dL) | 12.96±0.172 | 9.81±0.158* | 13.82±0.385# | 14.14±0.283# |
| WBC (×103 cells/µL) | 8.66±0.682 | 7.21±0.48 | 7.32±0.676 | 8.17±0.516 |
| Granulocytes (×103 cells/µL) | 1.28±0.098 | 1.04±0.073 | 1.22±0.145 | 1.3±0.278 |
| Lymphocytes (×103 cells/µL) | 7.04±0.549 | 6.62±0.458 | 7.33±0.267 | 7.85±0.289 |
| Monocytes (×103 cells/µL) | 1.11±0.103 | 1.05±0.05 | 1.11±0.115 | 0.88±0.068 |
| Platelets (×103 cells/µL) | 548.11±23.545 | 521.11±22.497 | 523.88±31.023 | 581.55±17.84 |
Notes: Data represent mean ± SEM of various hematological parameters,
*
P<0.01 compared to vehicle control,
#
P<0.01 compared to DOX control (n=6).
Abbreviations: DOX, doxorubicin; RUT, rutin; RBC, red blood cells; Hb, hemoglobin; WBC, white blood cells; SEM, standard error of the mean.