Table 5.

Acetylcholinesterase activity in brain

Treatment	Acetylcholinesterase activity (µM of acetylthiocholine hydrolyzed/min/mg of protein)
	Hippocampus	Frontal cortex
Vehicle control	8.275±0.403	9.819±0.514
DOX control	8.646±0.514	9.459±0.729
RUT + DOX	7.973±0.467	9.100±0.889
RUT	7.196±0.711	8.907±0.873

Notes: Data represent mean ± SEM of acetylcholinesterase enzyme activity in hippocampal and frontal cortex regions in brain (n=6). No significant difference observed between groups.

Abbreviations: DOX, doxorubicin; RUT, rutin; SEM, standard error of the mean.