. Author manuscript; available in PMC: 2018 Apr 15.

Published in final edited form as: Cancer. 2016 Dec 2;123(8):1372–1381. doi: 10.1002/cncr.30463

Table 5. Multivariate analysis of survival from diagnosis of stage IV melanoma.

	HR	95% CI	P value
Age	1.01	1.00-1.02	0.05
Gender
Female
Male	0.82	059-1.14	0.23
stage IV M1 classification
M1a
M1b	0.91	0.42-1.97	0.8
M1c	1.92	0.92-4.00	0.08
LDH
WNL
elevated	1.01	0.70-1.47	0.94
unknown	0.8	0.11-5.93	0.83
Mutation
BRAF^V600 mutation (vs BRAF^V600 ND)	0.93	0.64-1.34	0.7
NRAS mutation (vs NRAS ND)	1.2	0.82-1.76	0.35
BRAF^Non-V600 mutation (vs BRAF^Non-V600)	0.74	0.39-1.76	0.37
TP53 mutation (vs TP53 ND)	0.62	0.42-0.91	0.015

CI: confidence interval, HR: hazard ratio, LDH: lactate dehydrogenase, WNL: within normal limit, ND: not detected