Table 2.
Fixed effect | Estimateab | 95% CI | |
---|---|---|---|
• CF | −0.16 | −0.28 | −0.03 |
• Liver injury | 0.04 | −0.08 | 0.16 |
• Drugs increasing tacrolimus | −0.02 | −0.09 | 0.05 |
• ≥2 drugs increasing tacrolimus | −0.13 | −0.25 | 0.00 |
• 1 or 2 drugs decreasing tacrolimus | −0.06 | −0.13 | 0.01 |
• Day | 1.24 | 1.02 | 1.46 |
• Day squaredc | −0.13 | −0.15 | −0.10 |
aEstimate = regression coefficient in a linear mixed model, with log (tacrolimus concentration) as outcome variable
bEstimate of intercept = −0.19
cA quadratic term is included in the model because there was no linear relationship between outcome variable and factors included in the model