Table 5.
Toxicities
| Chemotherapy (n = 41) | Decitabine priming (n = 40) | p value | |
|---|---|---|---|
| Median duration of neutropenia (IQR; days) | 21 (16–35) | 22 (13–31) | 0.982 |
| Median duration of thrombocytopenia (IQR; days) | 26 (20–39) | 26 (19–35) | 0.752 |
| Grade 3 or 4, n (%) | |||
| Infection | 28 (68.3%) | 28 (70.0%) | 0.868 |
| Hemorrhage | 13 (31.7%) | 11 (27.5%) | 0.678 |
| Heart | 2 (4.9%) | 1 (2.5%) | – |
| Liver | 0 | 0 | – |
| Kidney | 0 | 0 | – |
| Rash | 1 (2.4%) | 1 (2.5%) | – |
Data for hematological toxicities (neutropenia and thrombocytopenia) were from the patients who had CR after treatment; neutropenia is defined as <1 × 109/L; thrombocytopenia is defined as <50 × 109/L