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. Author manuscript; available in PMC: 2017 Apr 8.
Published in final edited form as: J Card Fail. 2016 Jul 15;23(1):72–80. doi: 10.1016/j.cardfail.2016.07.429

Table 2.

Adenylyl Cyclase (AC) Expression (Mean (SD)) by Disease (Nonfailing [NF] Versus All Disease)

AC Isoform Adult NF Adult DCM Fold Change Effect Size P Value Ped NF LV Ped DCM Fold Change Effect Size P Value Ped NF RV Ped SRV Fold Change Effect Size P Value
AC2 0.472
(0.449)		 0.37
(0.235)		 −1.276 −0.003 .996 1.210
(0.724)		 2.899
(1.862)		   2.396   0.441 .007* 1.974
(1.548)		 2.816
(2.915)		   1.427   0.155 .432
AC3 2.579
(3.711)		 0.618
(0.516)		 −4.176 −0.173 .269 1.139
(0.521)		 0.783
(0.414)		 −1.455 −0.294 .069 1.226
(0.656)		 1.061
(0.833)		 −1.156 −0.186 .545
AC4 1.450
(1.145)		 0.934
(0.54)		 −1.552 −0.21   .189 1.076
(0.418)		 0.871
(0.408)		 −1.236 −0.191 .245 1.371
(0.738)		 1.679
(0.967)		   1.225   0.134 .504
AC5 1.500
(1.391)		 3.038
(2.570)		   2.025   0.247 .206 0.957
(0.288)		 1.225
(0.468)		   1.280   0.273 .098 1.079
(0.621)		 2.589
(1.594)		   2.399   0.589 .002*
AC6 1.218
(0.931)		 3.48
(2.629)		   2.857   0.386 .045* 1.083
(0.415)		 1.352
(0.810)		   1.248   0.116 .483 0.508
(0.217)		 0.488
(0.371)		 −1.041 −0.163 .439
AC7 0.332
(0.224)		 0.147
(0.060)		 −2.250 −0.427 .007* 1.173
(0.562)		 1.394
(0.634)		   1.188   0.089 .538 1.110
(0.49)		 0.691
(0.384)		 −1.606 −0.445 .020*
AC8 1.553
(1.397)		 1.113
(0.689)		 −1.395 −0.107 .501 1.308
(0.672)		 0.969
(0.499)		 −1.350 −0.227 .164 1.600
(1.108)		 1.269
(0.922)		 −1.261 −0.135 .502
AC9 1.927
(1.824)		 0.812
(0.478)		 −2.373 −0.262 .096 1.156
(0.575)		 0.859
(0.29)		 −1.347 −0.253 .125 1.116
(0.505)		 1.141
(0.805)		   1.022 −0.113 .504

DCM, dilated cardiomyopathy; other abbreviations as in Table 1.

*

P < .05 is considered significant.