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. 2017 Apr 8;10:21. doi: 10.1186/s12920-017-0257-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Diagram of TCA cycle and electron transport chain is shown, overlaid with gene expression results from GRMD versus wild type skeletal muscle samples. All listed genes, except for citrate synthase (CS), were differential between GRMD and wild type dogs, and each is colored according to direction of difference. Green genes represent those that were more highly expressed in wild type relative to GRMD dogs. Only two genes (ACLY and UCP2, colored in red) were more highly expressed in GRMD relative to control dogs