Table 4.

Effect of Late Intervention of Type 2 Diabetic Mice with Menhaden Oil, α-Lipoic Acid, Enalapril or their Combination on Motor and Sensory Nerve Conduction Velocity, Thermal Nociception and Intraepidermal Nerve Fiber Density

Determination	Baseline Control	Baseline Diabetic	Control	Diabetic	Diabetic + Menhaden Oil	Diabetic + α-Lipoic Acid	Diabetic + Enalapril	Diabetic + Combination
	(8)	(7)	(11)	(10)	(11)	(11)	(12)	(11)
MNCV (m/sec)	39.5 ± 1.6	26.6 ± 1.7^*	40.5 ± 1.2	26.2 ± 0.9^*	44.3 ± 2.3^†	34.6 ± 2.5	35.8 ± 2.5	44.4 ± 3.2^†
SNCV (m/sec)	30.4 ± 0.6	23.5 ± 0.7^*	25.9 ± 1.0	18.7 ± 0.3^*	25.5 ± 0.6^†	22.7 ± 1.2^†	23.3 ± 0.7^†	24.9 ± 0.5^†
Thermal nociception (sec)	5.1 ± 0.1	8.4 ± 0.2^*	5.2 ± 0.1	9.0 ± 0.2^*	6.1 ± 0.1^*, ^†	6.8 ± 0.1^*, ^†	6.4 ± 0.1^*, ^†	6.1 ± 0.2^*, ^†
INFD (profiles/mm)	24.7 ± 0.6	16.1 ± 0.6^*	26.0 ± 0.7	15.1 ± 0.4^*	22.3 ± 0.6^*, ^†	20.6 ± 0.5 ^*, ^†	21.9 ± 0.7^*, ^†	22.6 ± 0.6 ^*, ^†

Data are presented as the mean ± S.E.M.

P < 0.05 compared to respective control mice

^†

P < 0.05 compared to diabetic mice. Parentheses indicate the number of experimental animals.