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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Neuropharmacology. 2016 Dec 22;116:208–223. doi: 10.1016/j.neuropharm.2016.12.020

Figure 6.

Figure 6

Single unit electrophysiological recordings at cue onset or offset during a Pavlovian conditioning session. (A) Neuronal population activity in the OFC is presented as mean firing rate (±SEM, shaded) and normalized to whole session firing rate for nicotine-exposed (pink) and saline (blue) animals at cue onset and cue offset. (B, C) Phasic firing patterns of neurons that significantly changed their firing rate surrounding either cue offset or cue onset, for SAL (B) and NIC (C) groups. Green histograms represent cells that increased their firing rate, and blue histograms represent cells that decreased their firing rate, line thickness represents the proportion of cells displaying each phasic pattern. (*) significant difference in peak firing rate between groups, p<0.05.