Figure 9.
Single unit electrophysiological recordings at cue onset or offset during the saline test session. Neuronal population activity in the OFC is presented as mean firing rate (±SEM, shaded) and normalized to whole session firing rate for nicotine-exposed and saline-control animals at cue onset and cue offset. (A, B) Population firing rates in SAL animals on the saline test day (Panel A, blue histograms) and NIC animals (Panel B, pink histograms) compared to the baseline recording session depicted in Figure 6 (grey histograms). (C) Comparison of population activity from SAL (blue) and NIC (pink) animals on the saline test day. (*) significant difference in peak firing rate between groups, p<0.05.