Table 2.
Summary of sensitivity and subgroup analysis
| Model aspect varied | Base-case scenario | Sensitivity scenarios | Rationale |
|---|---|---|---|
| Unit cost for contact types defined as ‘other’ | Unit cost of £0.11, assuming that ‘other’ are undefined administrative tasks | Pooled weighted unit cost of £45.58 based on the recorded resource use for all contacts and associated unit costs excluding ‘other’ tasks | Whether these ‘other’ consultation types are administrative is uncertain |
| Duration of exacerbation period | 1 week | 3 days 2 weeks |
The average duration of symptoms for an exacerbation is uncertain |
| Utility decrement values for exacerbation | –0.1 (non-hospital) or –0.2 (hospitalisation) for exacerbation [20] | –0.216 relative to no exacerbation [19] | The utility decrement relative to no exacerbation is uncertain |
| Type of contacts included | All contacts regardless of whether they are respiratory related | Respiratory-related contacts | Contacts coded as respiratory related are more likely to be affected by the intervention, but a large proportion of contacts could not be coded as respiratory or non-respiratory related |
| QALY and cost-estimation period | QALYs estimated for 4 months and costs for 1 year post-intervention | QALYs estimated for 4 months and costs for 5 months post-intervention | To assess the shorter term (5 months) cost implications of the intervention |
| Age of population receiving intervention | Children aged 5–16 years | Children aged <5 years (children aged 4 years) | To assess the cost effectiveness of the intervention for children aged <5 years |
QALY quality-adjusted life-year