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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Drug Saf. 2017 Mar;40(3):263–272. doi: 10.1007/s40264-016-0490-1

Table 3.

Regression analyses of risk factors for multiple co-prescriptions of interacting drugs by different providers for varying constellation size.

Risk factor <5 providers
(n=32,944)
5 to 10 providers
(n=48,901)
>10 providers
(n=6,649)
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Age 1.05 (1.04 – 1.06) <0.0001 1.05 (1.04 – 1.05) <0.0001 1.03 (1.02 – 1.04) <0.0001
Charlson index 1.43 (1.32 – 1.56) <0.0001 1.30 (1.24 – 1.36) <0.0001 1.22 (1.15 – 1.30) <0.0001
Number of providers 1.44 (1.14 – 1.82)     0.002 1.24 (1.19 – 1.29) <0.0001 1.10 (1.07 – 1.13) <0.0001
Presence of PCP 1.16 (0.72 – 1.89)     0.545 1.14 (0.76 – 1.72)     0.517 1.07 (0.37 – 3.08)     0.900
Care density 0.85 (0.76 – 0.94)     0.002 0.80 (0.74 – 0.86) <0.0001 0.63 (0.55 – 0.72) <0.0001