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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Expert Opin Drug Deliv. 2016 Aug 8;14(3):427–446. doi: 10.1080/17425247.2016.1218464

Fig. 1.

Fig. 1

(a) Schematic diagram of PLGA NP for ratiometric co-delivery of GMP and cisplatin. (b) Tumor inhibition effects of free drugs, Combo free (cocktails of free drugs), cisplatin NP, GMP NP, Sepa NP (cocktails of single drug NP), and Combo NP in a stroma-rich UMUC3 bladder cancer xenograft model. Arrows indicate time of injection. The tumors were treated with three IV injections at a dose of 1.9 mg/kg cisplatin and 12 mg/kg GMP in all the treatment groups. Reprinted with permission from [7]. Copyright (2014) John Wiley and Sons.