Table 3. Hematology and serum chemistry values for male of Korl:ICR and other ICR mice at the age of 12 weeks.
| A:ICR | B:ICR | Korl:ICR | P - value | |||
|---|---|---|---|---|---|---|
| n=8 | n=8 | n=12 | A-B | A-Korl | B-Korl | |
| WBC (K/µL) | 5.47±2.48 | 4.65±3.95 | 4.97±1.4 | |||
| RBC (M/µL) | 9.24±0.54 | 10.03±0.82 | 9±0.79 | * | * | |
| HCT (%) | 55.34±4.08 | 62.13±6.42 | 50.76±3.9 | * | * | *** |
| MCV (fL) | 59.95±3.99 | 61.9±1.91 | 56.47±2.31 | * | *** | |
| MCH (pg) | 16.53±0.41 | 16.83±0.56 | 16.53±0.88 | |||
| MCHC (g/dL) | 27.66±1.84 | 27.24±1.69 | 29.26±1.38 | * | ** | |
| PLT (K/µL) | 1275±361.4 | 2147±539 | 979.7±299.8 | ** | *** | |
| MPV (fL) | 7.86±0.59 | 8.09±0.99 | 6.75±0.93 | ** | ** | |
| n=9 | n=9 | n=9 | ||||
| ALP (U/L) | 294.6±104.7 | 261.2±63.77 | 317.3±47.89 | |||
| ALT (U/L) | 29.78±7.26 | 29.22±4.94 | 33.33±10.97 | |||
| AST (U/L) | 100.7±57.22 | 70.11±21.35 | 88.11±25.39 | |||
| TP (g/dL) | 5.72±0.29 | 5.91±0.45 | 6.67±0.35 | *** | ** | |
| GLU (mg/dL) | 231.5±51.14 | 215.6±67 | 202.5±52.74 | |||
| HDL (mg/dL) | 101.2±15.61 | 102.8±12.88 | 116.3±20.38 | |||
| LDL (mg/dL) | 10.59±7.37 | 10.06±3.88 | 13.79±3.67 | |||
| BUN (mg/dL) | 22.32±2 | 26.74±4.82 | 21.71±3.58 | * | * | |
| CRE (mg/dL) | 0.42±0.05 | 0.37±0.05 | 0.44±0.03 | * | ||
| UA (mg/dL) | 6.68±1.46 | 6.54±1.9 | 7.73±2.13 | ** | ||
| ALB (g/dL) | 1.91±0.14 | 1.91±0.18 | 2.23±0.11 | *** | *** | |
| Ca2+ (mg/dL) | 11.44±0.79 | 12.35±0.61 | 13.41±0.85 | * | *** | ** |
The data shown represent the mean±SD (Student t-test, *P<0.05, **P<0.01, ***P<0.001).