TABLE 3.

Ability of group M consensus V3 peptides to absorb CON6 gp120- induced neutralizing activity to T-cell line-adapted HIV-1 MN and to HIV-1 primary isolates SS1196 and BX08

Guinea pig no.	HIV-1 Isolate	Neutralizing antibody titera
		Before absorption	After absorption	% Absorption
646	MN	6,166	2,309	63
647	MN	1,089	292	73
648	MN	1,364	195	86
649	MN	388	57	85
Mean ± SEM				77 ± 5
646	SS1196	1,408	406	68
647	SS1196	380	251	34
648	SS1196	469	195	58
649	SS1196	113	57	50
Mean ± SEM				53 ± 7
646	BX08	510	333	35
647	BX08	454	173	62
648	BX08	388	258	34
649	BX08	124	137	−10
Mean ± SEM				30 ± 15

^aNeutralizing titers are from the multiple-round luciferase assay as described in Materials and Methods.