Table 2.
Thyroid Hormone Levels and Biochemical Markers of Thyroid Function in Patient Groups Before and After Thyroidectomy
| Patient subgroups | ||||||
|---|---|---|---|---|---|---|
| TSH ≤0.03 μIU/mL (n = 58) | 0.03 < TSH ≤0.3 μIU/mL (n = 46) | 0.3 < TSH ≤5 μIU/mL (n = 29) | ||||
| Parameter | Before | After | Before | After | Before | After |
| Body weight (kg) | 56.5 (11.8) | 56.5 (11.6) | 61.4 (12.2) | 61.3 (13.3) | 59.6 (9.9) | 60.3 (9.9) |
| Heart rate (beats/min) | 68 (8) | 72 (9)c | 68 (11) | 66 (14) | 68 (11) | 71 (9) |
| Systolic BP (mmHg) | 121 (14) | 122 (16) | 122 (12) | 120 (20) | 127 (17) | 129 (23) |
| Diastolic BP (mmHg) | 74 (10) | 75 (11) | 76 (8) | 74 (10) | 78 (10) | 79 (13) |
| TSH (μIU/mL) | 1.48 (1.49) | 0.01 (0.01)c | 1.56 (1.96) | 0.07 (0.08)*c | 1.59 (1.20) | 1.51 (1.56) |
| fT4 (ng/dL) | 1.07 (0.14) | 1.56 (0.20)*c | 1.09 (0.11) | 1.45 (0.16)c | 1.12 (0.12) | 1.38 (0.17)c |
| fT3 (pg/mL) | 2.79 (0.33) | 3.17 (0.34)c | 2.92 (0.31) | 2.96 (0.31) | 2.92 (0.21) | 2.76 (0.24)a |
| Total-C (mg/dL) | 202 (34) | 197 (31) | 194 (29) | 192 (35) | 197 (32) | 202 (28) |
| Triglyceride (mg/dL) | 127 (67) | 121 (68) | 136 (70) | 126 (67) | 129 (61) | 123 (48) |
| HDL-C (mg/dL) | 63 (15) | 62 (14) | 63 (17) | 63 (20) | 63 (14) | 64 (11) |
| Non-HDL-C (mg/dL) | 139 (31) | 135 (28) | 131 (31) | 129 (34) | 134 (28) | 138 (26) |
| LDL-C (mg/dL) | 114 (27) | 111 (28) | 104 (26) | 104 (30) | 108 (26) | 114 (24)a |
| SHBG (nmol/L) | 69.2 (35.1) | 82.2 (40.6)c | 66.5 (37.6) | 66.9 (36.8) | 67.1 (34.9) | 71.7 (31.5) |
TSH values are shown as median (IQR). Other parameters are shown as mean (SD).
Statistical significance (before vs. after thyroidectomy) was analyzed by paired t-test or by *Wilcoxon signed rank test.
a
p < 0.05; bp < 0.01; cp < 0.001.
BP, blood pressure; fT4, free thyroxine; fT3, free triiodothyronine; total-C, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; SHBG, sex hormone-binding globulin; IQR, interquartile range.