Table 2.

RAI Status in Patients with Large NIFTP and At Least Two- or Four-Year FU^a

	No RAI		RAI		p-Value
Patients with at least two-year FU (n = 59)
n	32		27
Sex
Female	23	72%	17	63%	0.579
Male	9	28%	10	37%
Surgical procedure
Lobectomy	17	53%	0	0%	<0.001
Total/subtotal thyroidectomy	15	47%	27	100%
Sampling of NIFTP
Entirely/entire capsule	20	63%	14	52%	0.440
Representative	12	38%	13	48%
Sampling and status of lymph nodes
Not sampled	24	75%	18	67%	0.569
Benign lymph node(s)	8	25%	9	33%
Age, years, median (range)	50 (27–76)		49 (24–64)		0.517
Size, cm, median (range)	4.2 (4.0–5.8)		5.0 (4.0–7.5)		0.001
FU duration, years, median, mean (range)	7.5, 7.5 (2.4–20.5)		5.8, 6.8 (2.0–26.0)		0.181
Blocks sampled per cm of tumor if only representatively sampled, median (range)	2.2 (0.8–4.1)		2.0 (0.5–4.2)		0.614
Patients with at least four-year FU (n = 48)
n	25	100%	23	100%
Surgical procedure
Lobectomy	15	60%	0	0%	<0.001
Total/subtotal thyroidectomy	10	40%	23	100%
Size, cm, median (range)	4.2 (4.0–5.6)		5.0 (4.0–7.5)		0.001

^aAll values are expressed as n and % of column total unless otherwise specified.

^bp-Values are calculated using Fisher's exact test for categorical variables and a two-tailed Student's t-test for continuous variables.