Table 1. Inhibition assays showing the relative activity (%) of recombinant human DDO in the presence of different concentrations (1–1000 μM range) of first- (chlorpromazine, haloperidol) and second-generation antipsychotic (clozapine, olanzapine), and antidepressant drugs (amitriptyline, bupropion, fluoxetine).

Drug	Chemical structure	Concentration (μM)
		1	10	100	1000
Chlorpromazine		100	100	100	>90
Haloperidol		>95	>95	100	100
Clozapine		100	100	>95	>95
Olanzapine		97	81	10.4	2
Amitriptyline		100	100	100	100
Bupropion		>95	93	>95	89
Fluoxetine		100	>95	>95	100