Figure 4. Effects of jineol on melanogenesis in melan-a cells.

Cells were cultured with jineol (6.125–50 μM) for 3 days. (A) cytotoxicities, (B) melanin contents, and (C) tyrosinase activities were measured as described in Materials and Methods. Experiments were performed in triplicate, and results are presented as means ± SDs. *p < 0.05, **p < 0.01, student’s t-test. NT: No treatment; Arb: Arbutin.