Table 1.
Patient characteristics according to the study population
| All patients | Patients alive at 5 years | Patients treated with metastatic chemotherapy | ||||
|---|---|---|---|---|---|---|
| (n = 2165) | (n = 224) | (n = 1575) | ||||
| n | % | n | % | n | % | |
| Sex | ||||||
| Male | 1055 | 48.73 | 92 | 41.07 | 754 | 47.87 |
| Female | 1110 | 51.27 | 132 | 58.93 | 821 | 52.13 |
| Age at first metastasis | ||||||
| < 75 years old | 1886 | 87.11 | 216 | 96.43 | 1429 | 90.73 |
| ≥ 75 years old | 279 | 12.89 | 8 | 3.57 | 146 | 9.27 |
| Histology | ||||||
| Leiomyosarcoma | 502 | 23.19 | 60 | 26.79 | 396 | 25.14 |
| UPS | 203 | 9.38 | 9 | 4.02 | 141 | 8.95 |
| DLPS | 172 | 7.94 | 12 | 5.36 | 112 | 7.11 |
| Synovial sarcoma | 188 | 8.68 | 16 | 7.14 | 150 | 9.52 |
| MPNST | 80 | 3.70 | 11 | 4.91 | 50 | 3.17 |
| Other | 1020 | 47.11 | 116 | 51.79 | 726 | 46.10 |
| Grade | ||||||
| 1 | 138 | 6.37 | 48 | 21.43 | 94 | 5.97 |
| 2 | 590 | 27.25 | 74 | 33.04 | 440 | 27.94 |
| 3 | 1083 | 50.02 | 63 | 28.13 | 765 | 48.57 |
| Not available | 354 | 16.35 | 39 | 17.41 | 276 | 17.52 |
| Number of metastatic sites | ||||||
| 1 | 1780 | 82.22 | 199 | 88.84 | 1248 | 79.24 |
| > 1 | 385 | 17.78 | 25 | 11.16 | 327 | 20.76 |
| Metastatic sites | ||||||
| Lung | 1399 | 64.62 | 149 | 66.52 | 1075 | 68.25 |
| Liver | 410 | 18.94 | 34 | 15.18 | 352 | 22.35 |
| Peritoneum | 396 | 18.29 | 60 | 26.79 | 319 | 20.25 |
| Bone | 370 | 17.09 | 29 | 12.95 | 305 | 19.37 |
| Lymph node | 304 | 14.04 | 35 | 15.63 | 236 | 14.98 |
| Skin | 172 | 7.94 | 25 | 11.16 | 136 | 8.63 |
| Soft tissue | 173 | 7.99 | 36 | 16.07 | 135 | 8.57 |
| Pleura | 163 | 7.53 | 11 | 4.91 | 140 | 8.89 |
| Brain | 113 | 5.22 | 5 | 2.23 | 89 | 5.65 |
| Bone marrow | 12 | 0.55 | 0 | 0.00 | 10 | 0.63 |
| Other | 228 | 10.53 | 32 | 14.29 | 166 | 10.54 |
UPS undifferentiated pleomorphic sarcoma, DLPS dedifferentiated liposarcoma, MPNST malignant peripheral nerve sheath tumors