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Transcriptional activities of various HERV-K(HML-2) 5′ LTRs in Tera-1 (left) and T47D (right) cells, as determined by luciferase reporter gene assays. LTR activities are given as percentages of a positive control vector driven by a CMV promoter. Standard deviations are indicated for each LTR. basic, a negative control vector that lacked a promoter sequence. All tested LTRs were inactive in T47D cells, shown on the right, solely to illustrate this finding.
