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. 2017 Mar 31;12:634–647. doi: 10.1016/j.redox.2017.03.025

Fig. 7.

Fig. 7

Effect of curcumin and resveratrol on TRX1, TRXR1 and TXNIP mRNA levels and enzymatic activities in prostate cancer cells. LNCaP and PC-3 cells were incubated with 25 µM curcumin or 50 µM resveratrol for 48 h. Trx1 and TrxR1mRNA levels in LNCaP (A) and PC-3 (B) were analyzed by RT-qPCR. TRX (C) and TRXR (D) enzymatic activities were analyzed in LNCaP and PC-3 cells after 25 µM curcumin or 50 µM resveratrol for 48 h. Txnip mRNA levels (E) were analyzed by RT-qPCR. Graphs represent the mean ±SEM obtained from three independent experiments performed in triplicates. *p<0.05; #p<0.01; ***p<0.001 versus CON.