Table 1.
Correlation between ACSM3 expression and clinicopathological features in 235 HCC patients
| ACSM3 | |||
|---|---|---|---|
|
| |||
| Variable | Low (n=180) | High (n=55) | p-value |
| Sex | 0.486 | ||
| Male | 162 | 49 | |
| Female | 18 | 6 | |
| Age | 0.397 | ||
| ≤50 | 87 | 23 | |
| >50 | 93 | 32 | |
| HBsAg | 0.307 | ||
| Negative | 30 | 6 | |
| Positive | 148 | 48 | |
| Serum AFP | 0.042* | ||
| ≤20 ng/ml | 53 | 24 | |
| >20 ng/ml | 126 | 30 | |
| Liver cirrhosis | 0.459 | ||
| No | 59 | 21 | |
| Yes | 121 | 34 | |
| TNM | 0.799 | ||
| I | 57 | 18 | |
| II | 97 | 31 | |
| III-IV | 26 | 6 | |
| Child-pugh class | 0.328 | ||
| A | 165 | 48 | |
| B | 15 | 7 | |
| Tumor size | 0.323 | ||
| ≤3 cm | 78 | 28 | |
| >3 cm | 102 | 27 | |
| Tumor number | 0.239 | ||
| Single | 137 | 46 | |
| Multiple | 43 | 9 | |
| Tumor differentiation | 0.307 | ||
| Well | 12 | 7 | |
| Moderate | 167 | 48 | |
| Poor | 1 | 0 | |
| Vascular invasion | 0.400 | ||
| No | 64 | 23 | |
| Yes | 116 | 32 | |
Abbreviations: HCC, hepatocellular carcinoma; HBsAg, hepatitis B surface antigen; AFP, α-fetoprotein; TNM, tumor-nodes-metastases.