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. 2017 Mar 1;7(3):688–699.

Table 3.

The association between relative expression level of 4 lncRNAs and clinicopathologic characteristics

EMP1-008 ATF3-008 RCOR3-013 TMEM63A-005

Variable N Mean SD 95% CI Mean SD 95% CI Mean SD 95% CI Mean SD 95% CI




P. value P. value P. value P. value
Age (y)
    < 60 19 2.63 4.51 (-3.14, 3.60) -0.09 3.54 (-1.43, 3.58) 1.34 3.57 (-2.33, 2.58) 0.47 1.99 (-1.653, 1.777)
    ≥ 60 13 2.4 4.68 0.89 -1.17 3.19 0.388 1.22 2.98 0.917 0.41 2.77 0.941
Gender
    F 15 1.82 4.85 (-4.62, 1.94) -0.02 3.72 (-1.51, 3.43) 0.71 3.4 (-3.47, 1.30) 0.35 1.77 (-1.869, 1.504)
    M 17 3.16 4.23 0.412 -0.98 3.12 0.431 1.8 3.21 0.359 0.53 2.73 0.826
Adbominal_pain
    0 18 2.61 4.33 (-3.16, 3.51) -0.82 3.03 (-3.17, 1.83) 0.83 2.99 (-3.46, 1.34) 0 2.5 (-2.672, 0.638)
    1 14 2.44 4.89 0.917 -0.15 3.89 0.586 1.89 3.66 0.374 1.02 1.93 0.219
Cirrhosis
    0 26 2.71 4.69 (-3.28, 5.17) -0.87 3.55 (-4.94, 1.29) 1.02 3.5 (-4.49, 1.60) 0.81 1.91 (-0.079, 3.984)
    1 6 1.77 3.9 0.652 0.95 2.23 0.241 2.47 1.95 0.34 -1.14 3.27 0.059
Hepatitis
    0 18 2.52 4.48 (-3.37, 3.30) -0.94 3.36 (-3.42, 1.55) 1 3.11 (-3.09, 1.75) 0.49 2.14 (-1.597, 1.798)
    1 14 2.55 4.72 0.983 0 3.49 0.448 1.67 3.59 0.575 0.39 2.56 0.905
CA199 (U/ml)
    0 (< 40) 14 2.75 4.31 (-2.96, 3.71) 0.16 3.07 (-1.25, 3.69) 1.36 3.39 (-2.32, 2.55) -0.23 2.31 (-2.848, 0.426)
    1 (≥ 40) 18 2.37 4.78 0.819 -1.06 3.62 0.321 1.24 3.31 0.923 0.98 2.2 0.141
AFP (IU/ml)
    0 (< 20) 26 2.74 4.6 (-3.13, 5.31) -0.32 3.66 (-2.06, 4.27) 1.58 3.39 (-1.53, 4.55) 0.78 1.69 (-0.31, 3.80)
    1 (≥ 20) 6 1.65 4.37 0.603 -1.42 1.78 0.482 0.07 2.73 0.319 -0.97 3.93 0.094
CEA (ng/ml)
    0 (< 5) 27 2.11 4.67 (-7.16, 1.73) -0.75 3.25 (-4.79, 1.99) 1.18 3.4 (-4.03, 2.60) 0.32 2.39 (-3.11, 1.49)
    1 (≥ 5) 5 4.82 2.86 0.222 0.65 4.33 0.407 1.89 2.9 0.664 1.13 1.71 0.48
CA125 (U/ml)
    0 (< 35) 22 2.9 4.04 (-2.38, 4.70) -0.73 2.98 (-3.31, 2.04) 1.19 2.97 (-2.92, 2.29) 0.36 2.42 (-2.086, 1.543)
    1 (≥ 35) 10 1.74 5.56 0.509 -0.09 4.32 0.633 1.51 4.08 0.807 0.64 2.1 0.762
CA153 (U/ml)
    0 (< 25) 26 2.59 4.2 (-3.92, 4.55) -0.2 3.17 (-1.37, 4.87) 1.01 2.91 (-4.54, 1.54) 0.68 1.88 (-0.86, 3.35)
    1 (≥ 25) 6 2.28 6.13 0.88 -1.95 4.27 0.261 2.51 4.77 0.322 -0.56 3.67 0.236
CA724 (U/ml)
    0 (< 10) 27 2.43 4.5 (-5.22, 3.88) -0.73 3.34 (-4.66, 2.14) 1.12 3.38 (-4.38, 2.22) 0.71 1.89 (-0.59, 3.88)
    1 (≥ 10) 5 3.1 5.03 0.765 0.54 3.85 0.454 2.2 2.92 0.509 -0.94 3.84 0.144
CA242 (U/ml)
    0 (< 20) 19 3 3.98 (-2.18, 4.50) 0.07 3.3 (-1.00, 3.95) 1.5 3.12 (-1.94, 2.96) 0.4 2.27 (-1.840, 1.589)
    1 (≥ 20) 13 1.85 5.28 0.485 -1.41 3.47 0.233 0.99 3.63 0.673 0.52 2.42 0.882
Tumor_size (cm)
    0 (< 5) 16 3.32 4.37 (-1.69, 4.83) 0.1 2.99 (-1.19, 3.70) 1.09 2.69 (-2.81, 2.01) 0.9 1.62 (-0.743, 2.557)
    1 (> 5) 16 1.75 4.65 0.332 -1.16 3.74 0.304 1.49 3.88 0.739 0 2.8 0.271
Tumor_metastasis
    0 21 3.95 4.15 (0.99, 7.24) 0.79 3.13 (1.63, 6.03) 2.19 3.14 (0.28, 4.97) 0.43 2.39 (-1.823, 1.724)
    1 11 -0.17 4.05 0.012 -3.04 2.35 0.001 -0.43 2.98 0.03 0.48 2.22 0.955
Tumor_number
    Single 21 2.48 4.44 (-3.65, 3.32) -0.6 3.24 (-2.83, 2.41) 1.51 3.38 (-1.90, 3.16) 0.24 1.99 (-2.357, 1.161)
    Mulitple 11 2.64 4.86 0.925 -0.39 3.84 0.869 0.88 3.23 0.613 0.84 2.85 0.493
HBsAg
    0 24 2.59 4.28 (-3.62, 4.02) -0.78 3.28 (-3.84, 1.86) 1.26 3.25 (-2.92, 2.66) 0.51 2.39 (-1.709, 2.178)
    1 8 2.38 5.47 0.914 0.21 3.84 0.484 1.39 3.63 0.926 0.27 2.11 0.807
CK18
    0 18 1.67 4.18 (-5.23, 1.27) -1.66 3.12 (-4.90, -0.26) 0.97 3.17 (-3.16, 1.68) 0.12 2.73 (-2.422, 0.928)
    1 14 3.65 4.82 0.223 0.92 3.27 0.03 1.71 3.51 0.535 0.87 1.57 0.37
CK19
    0 25 2.29 4.62 (-5.11, 2.86) -0.91 3.28 (-4.68, 1.20) 1.2 3.28 (-3.34, 2.49) 0.18 2.49 (-3.204, 0.768)
    1 7 3.41 4.31 0.568 0.83 3.7 0.237 1.63 3.56 0.767 1.4 1.06 0.22
CD10
    0 24 2.4 4.39 (-4.33, 3.30) -0.37 3.49 (-2.24, 3.49) 1.53 3.13 (-1.82, 3.71) 0.79 1.85 (-0.495, 3.257)
    1 8 2.92 5.15 0.784 -1 3.26 0.66 0.59 3.86 0.492 -0.59 3.23 0.143
OPN
    0 17 1.91 4.89 (-4.62, 1.94) -0.64 3.38 (-2.72, 2.27) 1.21 3.13 (-2.59, 2.24) 0.19 2.15 (-2.236, 1.114)
    1 15 3.24 4.08 0.412 -0.41 3.52 0.854 1.39 3.57 0.883 0.75 2.49 0.499