Table 3.
The association between relative expression level of 4 lncRNAs and clinicopathologic characteristics
| EMP1-008 | ATF3-008 | RCOR3-013 | TMEM63A-005 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Variable | N | Mean | SD | 95% CI | Mean | SD | 95% CI | Mean | SD | 95% CI | Mean | SD | 95% CI |
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| P. value | P. value | P. value | P. value | ||||||||||
| Age (y) | |||||||||||||
| < 60 | 19 | 2.63 | 4.51 | (-3.14, 3.60) | -0.09 | 3.54 | (-1.43, 3.58) | 1.34 | 3.57 | (-2.33, 2.58) | 0.47 | 1.99 | (-1.653, 1.777) |
| ≥ 60 | 13 | 2.4 | 4.68 | 0.89 | -1.17 | 3.19 | 0.388 | 1.22 | 2.98 | 0.917 | 0.41 | 2.77 | 0.941 |
| Gender | |||||||||||||
| F | 15 | 1.82 | 4.85 | (-4.62, 1.94) | -0.02 | 3.72 | (-1.51, 3.43) | 0.71 | 3.4 | (-3.47, 1.30) | 0.35 | 1.77 | (-1.869, 1.504) |
| M | 17 | 3.16 | 4.23 | 0.412 | -0.98 | 3.12 | 0.431 | 1.8 | 3.21 | 0.359 | 0.53 | 2.73 | 0.826 |
| Adbominal_pain | |||||||||||||
| 0 | 18 | 2.61 | 4.33 | (-3.16, 3.51) | -0.82 | 3.03 | (-3.17, 1.83) | 0.83 | 2.99 | (-3.46, 1.34) | 0 | 2.5 | (-2.672, 0.638) |
| 1 | 14 | 2.44 | 4.89 | 0.917 | -0.15 | 3.89 | 0.586 | 1.89 | 3.66 | 0.374 | 1.02 | 1.93 | 0.219 |
| Cirrhosis | |||||||||||||
| 0 | 26 | 2.71 | 4.69 | (-3.28, 5.17) | -0.87 | 3.55 | (-4.94, 1.29) | 1.02 | 3.5 | (-4.49, 1.60) | 0.81 | 1.91 | (-0.079, 3.984) |
| 1 | 6 | 1.77 | 3.9 | 0.652 | 0.95 | 2.23 | 0.241 | 2.47 | 1.95 | 0.34 | -1.14 | 3.27 | 0.059 |
| Hepatitis | |||||||||||||
| 0 | 18 | 2.52 | 4.48 | (-3.37, 3.30) | -0.94 | 3.36 | (-3.42, 1.55) | 1 | 3.11 | (-3.09, 1.75) | 0.49 | 2.14 | (-1.597, 1.798) |
| 1 | 14 | 2.55 | 4.72 | 0.983 | 0 | 3.49 | 0.448 | 1.67 | 3.59 | 0.575 | 0.39 | 2.56 | 0.905 |
| CA199 (U/ml) | |||||||||||||
| 0 (< 40) | 14 | 2.75 | 4.31 | (-2.96, 3.71) | 0.16 | 3.07 | (-1.25, 3.69) | 1.36 | 3.39 | (-2.32, 2.55) | -0.23 | 2.31 | (-2.848, 0.426) |
| 1 (≥ 40) | 18 | 2.37 | 4.78 | 0.819 | -1.06 | 3.62 | 0.321 | 1.24 | 3.31 | 0.923 | 0.98 | 2.2 | 0.141 |
| AFP (IU/ml) | |||||||||||||
| 0 (< 20) | 26 | 2.74 | 4.6 | (-3.13, 5.31) | -0.32 | 3.66 | (-2.06, 4.27) | 1.58 | 3.39 | (-1.53, 4.55) | 0.78 | 1.69 | (-0.31, 3.80) |
| 1 (≥ 20) | 6 | 1.65 | 4.37 | 0.603 | -1.42 | 1.78 | 0.482 | 0.07 | 2.73 | 0.319 | -0.97 | 3.93 | 0.094 |
| CEA (ng/ml) | |||||||||||||
| 0 (< 5) | 27 | 2.11 | 4.67 | (-7.16, 1.73) | -0.75 | 3.25 | (-4.79, 1.99) | 1.18 | 3.4 | (-4.03, 2.60) | 0.32 | 2.39 | (-3.11, 1.49) |
| 1 (≥ 5) | 5 | 4.82 | 2.86 | 0.222 | 0.65 | 4.33 | 0.407 | 1.89 | 2.9 | 0.664 | 1.13 | 1.71 | 0.48 |
| CA125 (U/ml) | |||||||||||||
| 0 (< 35) | 22 | 2.9 | 4.04 | (-2.38, 4.70) | -0.73 | 2.98 | (-3.31, 2.04) | 1.19 | 2.97 | (-2.92, 2.29) | 0.36 | 2.42 | (-2.086, 1.543) |
| 1 (≥ 35) | 10 | 1.74 | 5.56 | 0.509 | -0.09 | 4.32 | 0.633 | 1.51 | 4.08 | 0.807 | 0.64 | 2.1 | 0.762 |
| CA153 (U/ml) | |||||||||||||
| 0 (< 25) | 26 | 2.59 | 4.2 | (-3.92, 4.55) | -0.2 | 3.17 | (-1.37, 4.87) | 1.01 | 2.91 | (-4.54, 1.54) | 0.68 | 1.88 | (-0.86, 3.35) |
| 1 (≥ 25) | 6 | 2.28 | 6.13 | 0.88 | -1.95 | 4.27 | 0.261 | 2.51 | 4.77 | 0.322 | -0.56 | 3.67 | 0.236 |
| CA724 (U/ml) | |||||||||||||
| 0 (< 10) | 27 | 2.43 | 4.5 | (-5.22, 3.88) | -0.73 | 3.34 | (-4.66, 2.14) | 1.12 | 3.38 | (-4.38, 2.22) | 0.71 | 1.89 | (-0.59, 3.88) |
| 1 (≥ 10) | 5 | 3.1 | 5.03 | 0.765 | 0.54 | 3.85 | 0.454 | 2.2 | 2.92 | 0.509 | -0.94 | 3.84 | 0.144 |
| CA242 (U/ml) | |||||||||||||
| 0 (< 20) | 19 | 3 | 3.98 | (-2.18, 4.50) | 0.07 | 3.3 | (-1.00, 3.95) | 1.5 | 3.12 | (-1.94, 2.96) | 0.4 | 2.27 | (-1.840, 1.589) |
| 1 (≥ 20) | 13 | 1.85 | 5.28 | 0.485 | -1.41 | 3.47 | 0.233 | 0.99 | 3.63 | 0.673 | 0.52 | 2.42 | 0.882 |
| Tumor_size (cm) | |||||||||||||
| 0 (< 5) | 16 | 3.32 | 4.37 | (-1.69, 4.83) | 0.1 | 2.99 | (-1.19, 3.70) | 1.09 | 2.69 | (-2.81, 2.01) | 0.9 | 1.62 | (-0.743, 2.557) |
| 1 (> 5) | 16 | 1.75 | 4.65 | 0.332 | -1.16 | 3.74 | 0.304 | 1.49 | 3.88 | 0.739 | 0 | 2.8 | 0.271 |
| Tumor_metastasis | |||||||||||||
| 0 | 21 | 3.95 | 4.15 | (0.99, 7.24) | 0.79 | 3.13 | (1.63, 6.03) | 2.19 | 3.14 | (0.28, 4.97) | 0.43 | 2.39 | (-1.823, 1.724) |
| 1 | 11 | -0.17 | 4.05 | 0.012 | -3.04 | 2.35 | 0.001 | -0.43 | 2.98 | 0.03 | 0.48 | 2.22 | 0.955 |
| Tumor_number | |||||||||||||
| Single | 21 | 2.48 | 4.44 | (-3.65, 3.32) | -0.6 | 3.24 | (-2.83, 2.41) | 1.51 | 3.38 | (-1.90, 3.16) | 0.24 | 1.99 | (-2.357, 1.161) |
| Mulitple | 11 | 2.64 | 4.86 | 0.925 | -0.39 | 3.84 | 0.869 | 0.88 | 3.23 | 0.613 | 0.84 | 2.85 | 0.493 |
| HBsAg | |||||||||||||
| 0 | 24 | 2.59 | 4.28 | (-3.62, 4.02) | -0.78 | 3.28 | (-3.84, 1.86) | 1.26 | 3.25 | (-2.92, 2.66) | 0.51 | 2.39 | (-1.709, 2.178) |
| 1 | 8 | 2.38 | 5.47 | 0.914 | 0.21 | 3.84 | 0.484 | 1.39 | 3.63 | 0.926 | 0.27 | 2.11 | 0.807 |
| CK18 | |||||||||||||
| 0 | 18 | 1.67 | 4.18 | (-5.23, 1.27) | -1.66 | 3.12 | (-4.90, -0.26) | 0.97 | 3.17 | (-3.16, 1.68) | 0.12 | 2.73 | (-2.422, 0.928) |
| 1 | 14 | 3.65 | 4.82 | 0.223 | 0.92 | 3.27 | 0.03 | 1.71 | 3.51 | 0.535 | 0.87 | 1.57 | 0.37 |
| CK19 | |||||||||||||
| 0 | 25 | 2.29 | 4.62 | (-5.11, 2.86) | -0.91 | 3.28 | (-4.68, 1.20) | 1.2 | 3.28 | (-3.34, 2.49) | 0.18 | 2.49 | (-3.204, 0.768) |
| 1 | 7 | 3.41 | 4.31 | 0.568 | 0.83 | 3.7 | 0.237 | 1.63 | 3.56 | 0.767 | 1.4 | 1.06 | 0.22 |
| CD10 | |||||||||||||
| 0 | 24 | 2.4 | 4.39 | (-4.33, 3.30) | -0.37 | 3.49 | (-2.24, 3.49) | 1.53 | 3.13 | (-1.82, 3.71) | 0.79 | 1.85 | (-0.495, 3.257) |
| 1 | 8 | 2.92 | 5.15 | 0.784 | -1 | 3.26 | 0.66 | 0.59 | 3.86 | 0.492 | -0.59 | 3.23 | 0.143 |
| OPN | |||||||||||||
| 0 | 17 | 1.91 | 4.89 | (-4.62, 1.94) | -0.64 | 3.38 | (-2.72, 2.27) | 1.21 | 3.13 | (-2.59, 2.24) | 0.19 | 2.15 | (-2.236, 1.114) |
| 1 | 15 | 3.24 | 4.08 | 0.412 | -0.41 | 3.52 | 0.854 | 1.39 | 3.57 | 0.883 | 0.75 | 2.49 | 0.499 |