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Gel shift assay of cESG-siRNA complexes confirms condensation of siRNA to cESG. Following condensation reactions, complexes were loaded into wells of 1% agarose gel, followed by electrophoresis. Migration of free siRNA (arrow) was observed in formulations with a higher numbers of siRNA per cESG. Impeded migration (asterisks), indicative of siRNA condensation, is observed in wells containing 200 siRNA per particle or less.
