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. 2017 Mar 27;2017:4695491. doi: 10.1155/2017/4695491

Table 1.

Previous reports of patients with acute basophilic leukemia or acute myeloid leukemia with basophilic differentiation transformed from myelodysplastic syndrome. M, male; F, female; RA, refractory anemia; RAEB, refractory anemia with excess blasts; RCMD, refractory cytopenia with multilineage dysplasia; ND, not described; IP, interstitial pneumonia.

Case Age/sex Diagnosis Interval from diagnosis to transformation Karyotype at transformation Outcome prognosis from transformation Reference
1 52/F RAEB 2 months Complex karyotype including -7 Death of disease 6 months Shirakawa et al., 1992
2 52/F RA 2 years del(5)(q31q35) Death due to IP 2 months Yamagata et al., 1995
3 84/F ND 2 months Complex karyotype including -7 ND ND Wells et al., 2014
4 64/M RCMD 2 months Complex karyotype including -7 ND ND Bahmanyar and Chang, 2016
5 81/M RAEB-1 3 months -7, add(1)(q21) Death of bronchopneumonia 6 months This case