Table 2.
Sequential Organ Failure Assessment (SOFA) score(4)
| Score | 1 | 2 | 3 | 4 |
|---|---|---|---|---|
| Respiratory system (PaO2/FiO2 - mmHg) | < 400 | < 300 | < 200 (and ventilation support) |
< 100 (and ventilation support) |
| Coagulation (platelets x 103/mm3) | < 150 | < 100 | < 50 | < 20 |
| Liver (bilirubin - mg/dL) | 1.2 - 1.9 | 2.0 - 5.9 | 6.0 - 11.9 | > 12.0 |
| Cardiovascular system (arterial hypotension)* | MAP < 70mmHg | Dopamine ≤ 5 or dobutamine (any dose) |
Dopamine > 5 or epinephrine ≤ 0.1 or norepinephrine ≤ 0.1 |
Dopamine > 15 or epinephrine > 0.1. or norepinephrine > 0.1 |
| Central nervous system (Glasgow Coma Scale) | 13 - 14 | 10 - 12 | 6 - 9 | < 6 |
| Kidneys (creatinine - mg/dL) or urine output - mL/day | 1.2 - 1.9 | 2.0 - 3.4 | 3.5 - 4.9 or < 500mL/day |
> 5.0 or < 200mL/day |
*
Adrenergic agents must be administered for ≥ 1 hour; doses are expressed as µg/kg/minute; PaO2/FiO2 - partial pressure of oxygen/fraction of inspired oxygen; MAP - mean arterial pressure.