Fig. 6.

Depression of mitogen-activated protein kinase (MAPK) pathway by black ginseng-enriched Chong-Myung-Tang (CMT) extracts. Protein extraction, running, transferring, and analyzation were carried out according to the procedure followed for the nuclear factor-κB (NF-κB) pathway. Images are representative of at least three independent experiments. Data are mean ± standard deviation (n = 3); *p < 0.01, **p < 0.005, ***p < 0.001 compared with lipopolysaccharide only. (A and B) Phosphorylation of extracellular signal-regulated kinase (P-ERK), Jun amino-terminal kinase (P-JNK), and p38 (P-p38) compared with (Total form of extracellular signal regulated kinase) (T-ERK), Total form of c-Jun-n-terminal kinase (T-JNK), and Total form of p38 (T-p38), respectively. (C and D) Phosphorylation of MKK (P-MKK) compared with T-MKK. Phosphorylation of MEK (P-MEK) compared with T-MEK. MEK/MKK, mitogen-activated protein kinase kinase.