Table 2.
Effect of ginseng berry extract (GBx) supplementation on blood coagulation in rats fed high fat diet
| CON | HFD | HFD supplemented with |
|||
|---|---|---|---|---|---|
| GBx 50 | GBx 100 | GBx 150 | |||
| PT (s) | 17.75 ± 0.74 | 15.66 ± 1.05* | 16.52 ± 0.60*,** | 16.75 ± 0.89*,** | 16.65 ± 0.52*,** |
| aPTT (s) | 17.62 ± 0.09 | 17.88 ± 0.47 | 17.99 ± 0.59 | 18.70 ± 0.87*,** | 18.43 ± 1.09* |
| Col/EPI (s) | 300.00 ± 0.00 | 289.70 ± 2.57 | 300.00 ± 0.00 | 300.00 ± 0.00 | 289.05 ± 4.15 |
| Col/ADP (s) | 260.33 ± 1.40 | 263.80 ± 9.03 | 300.00 ± 0.00 | 298.80 ± 3.79 | 293.33 ± 8.73 |
| TXA2 (pg/mL) | 295.87 ± 55.32 | 520.12 ± 25.12* | 459.61 ± 80.55* | 81.06 ± 10.48*,** | 73.60 ± 10.36*,** |
| Serotonin (pg/mL) | 108.43 ± 16.55 | 126.63 ± 10.93 | 116.12 ± 15.85 | 95.08 ± 5.38 | 64.85 ± 10.96*,** |
| FDP (pg/mL) | 574.29 ± 35.36 | 554.01 ± 52.55 | 667.23 ± 48.18 | 1182.36 ± 92.31*,** | 1053.94 ± 94.81*,** |
Values are reported as the means ± standard deviation.
* p < 0.05 versus CON group.
** p < 0.05 versus HFD group.
aPTT, activated partial thromboplastin time; Col/ADP, collagen/adenosine-5-diphosphate; Col/EPI, collagen/epinephrine; CON, control group; FDP, fibrinogen degradation products; GBx 50, 100, 150, groups treated with GB extract 50 mg/kg, 100 mg/kg, or 150 mg/kg body weight together with a HFD; HFD, high-fat diet group; PT, prothrombin time; TXA2, thromboxane A2.