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. 2016 Feb 19;41(2):134–143. doi: 10.1016/j.jgr.2016.02.003

Fig. 2.

Fig. 2

Effects of Korean Red Ginseng extract (RGE) on chemokine expression in skin lesions and serum immunoglobulin E (IgE) and interleukin-6 (IL-6) levels. (A) mRNA levels of IL-8, thymus and activation-regulated chemokine (TARC), and macrophage-derived chemokine (MDC) in skin lesions. Total RNA was isolated from normal or 1-fluoro-2,4-dinitrobenzene (DNFB)-induced dermatitis dorsal skin. (B and C) Blood samples were collected from the mice, and the levels of serum IgE (B) and IL-6 (C) in the indicated groups were measured with the enzyme-linked immunosorbent assay (ELISA) method. Values represent the mean ± standard deviation (SD) of three independent experiments. *p < 0.05 versus blank and **p < 0.05, ***p < 0.01 versus DNFB alone. Blank, DNFB-untreated normal mice; DNFB, DNFB-treated atopic dermatitis (AD) mice; RGE, DNFB-treated AD mice administered RGE after 4 wk of DNFB treatment; Pre-RGE, DNFB-treated AD mice administered RGE after the first DNFB treatment.