Effect of FBG on renal histological changes and protein expressions of renal cortex tissues. (A) PAS staining of representative renal section and its quantitative data for the tubular damage. (B) NF-κB/p65, COX-2, and cleaved caspase-3 protein expressions. (C) Quantitative data for the COX-2 Western blot analysis of renal cortex tissues. (D) Quantitative data for the cleaved caspase-3 Western blot analysis of renal cortex tissues. (E) Quantitative data for the NF-κB/p65 Western blot analysis of renal cortex tissues. Kidney samples were fixed, dehydrated, embedded in paraffin, sectioned at 3-μm thickness, and stained with PAS reagents for histological examination. Proteins from kidneys were separated by SDS-PAGE, transferred to PVDF membranes, and it was analyzed for NF-κB/p65, COX-2 and cleaved caspase-3. * p < 0.05 compared to the cisplatin-treated control value. FBG, fermented black ginseng; PAS, periodic acid-Schiff; PVDF, polyvinylidene fluoride; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis.