Table 1.
Literature review of cerebral infarction resulting from takotsubo cardiomyopathy
| Authors, year | Age /Sex | Trigger event | Tc symptoms | Stroke symptoms | Tc to stroke | Thrombus (Resolved) | Treatment prior to stroke | Treatment post stroke |
|---|---|---|---|---|---|---|---|---|
| Matsuoka et al., 2004 | 57, F | NA | None | Palsy of rt. arm | 2 days | Present (4 weeks later) | None | AC |
| Grabowski et al., 2007 | 85, F | NA | None | Palsy of rt. arm | NA | Absent | None | NA |
| 64, F | NA | None | Motor aphasia | NA | Present | None | AC | |
| De Gregorio et al., 2008 | 74, F | Physical stress | Dyspnea, fatigue | Dysphasia, palsy of right arm | NA | Present (2 weeks later) | None | AC |
| Mitsuma et al., 2008 | 83, F | None | Chest pain | Consciousness disorder, hemiparesis | > 48 hours | Absent | NA | AC |
| 81, F | Emotional stress | Chest discomfort | Dysphemia, hemiparesis | > 48 hours | Absent | NA | AC | |
| Schmidt et al., 2009 | 70, F | NA | Dyspnea, chest discomfort | Sensory aphasia | 3 days | Present (3 months later) | AC | AC |
| Jabiri et al., 2010 | 55, F | Emotional stress | Chest pain | Lt. hemiparesis | 4 days | Absent | None | rt-PA |
| Shin et al., 2011 | 76, F | NA | Nausea, abdominal discomfort | Consciousness disorder | 10 days | Present (1 week later) | None | AC |
| Yonekawa et al., 2011 | 61, F | Physical stress | NA | Palsy of lt. hand | 7 days | Present | None | AC |
| Kurisu et al., 2011 | 82, F | NA | None | Consciousness disorder | NA | Present | AC | NA |
| Lee et al., 2011 | 43, F | Emotional stress | Chest pain diaphoresis | Nausea, vomiting | The same day | Absent | None | AC |
| Yaylali et al., 2012 | 81, F | Physical stress | Nausea | Lt. Hemiparesis | NA | Absent | AC* | AP |
| Kim et al., 2012 | NA | Emotional stress | NA | NA | NA | Present | NA | AC |
| Matsuzono et al., 2013 | 71, F | Physical stress | None | Rt. Hemiparesis | 5 days | Present | AC | AC |
| Young et al., 2014 | 68, F | Physical stress | NA | Consciousness disorder | 5 days | Absent | None | NA |
| 80, F | None | Dyspnea | NA | 13 days | Absent | None | NA | |
| 85, F | Physical stress | Chest pain | NA | 2 days | Absent | AC** | NA | |
| 84, F | Emotional stress | Chest pain | NA | 2 days | Absent | AP*** | NA |
AC: Anticoagulant therapy, AP: Antiplatelet therapy, TC: Takotsubo cardiomyopathy,
*
Discontinued before stroke onset because of side effects,
**
Had a history of atrial fibrillation and took anticoagulant therapy prior to admission,
***
Had a history of stroke and took aspirin prior to admission.