| 2009 |
Rizvi et al., 200939
|
5 - 30 µM |
30 minutes up to 72 hours |
Characterization of SMIFH2 in Fission yeast, NIH3T3 mouse fibroblasts and A549 human lung adenocarcinoma epithelial cells |
| 2011 |
Poincloux et al., 201149
|
25 µM |
up to 4 hours |
To study Formin-dependent invasive capacities of MDA-MB-231 human breast carcinoma cells |
| Li et al., 201143
|
100 nM |
not specified |
To study the relationship between Formin function and melanoblast motility |
| 2012 |
Tang and Brieher, 201253
|
not specified |
30 minutes |
To study the contribution of Formins during actin recovery in apical junctions of polarized MDCK cells after Latrunculin B treatment |
| Wyse et al., 201256
|
10 µM |
~63 minutes |
To study the role of mDia Formins in CXCL12-induced bleb formation in MDA-MB-231 human breast carcinoma cells |
| Oakes et al., 201247
|
10 – 15 µM |
>4 hours |
To confirm a previous study that formation of radial stress fibres formation in U2OS cells is Formin Dia1-dependent |
| Miklavc et al., 201245
|
25 µM |
not specified |
To show that actin coat formation on lamellar bodies in alveolar type II cells are Formin-dependent |
| Chin et al., 201260
|
10 µM |
4 hours |
To study the role of Formin-mediated cytoskeletal signaling in Chlamydia bacterial inclusion and extrusion from host cells (HeLa cells) |
| Rosero et al., 201251
|
5 - 30 µM |
72 hours |
To study the plant cell growth and morphogenesis of Arabidopsis plants |
| 2013 |
Sandbo et al., 201352
|
3 - 30 µM |
30 minutes |
To study myofibroblast differentation in human lung fibroblast cells |
| Fritzsche et al., 201365
|
40 µM |
30 minutes |
To analyse the contribution of Formin-mediated actin polymerization on actin cortex homeostasis |
| Goldspink et al., 201340
|
10 µM |
40 minutes |
To show that microtubule reorganization of EB-2 depleted ARPE-19 cells are restored to normal upon Formin inhibition |
| Wilson et al., 201355
|
40 µM |
up to 490 seconds |
To study the contribution of Formin-mediated actin polymerization at the leading edge of polarized HL60 neutrophil-like cells during 3D migration |
| Rao et al., 201350
|
30 µM |
3 hours |
As a negative control that activation of endogenous Diaphanous-related Formins by photoactivatable-DAD construct is indeed Formin dependent |
| Aragona et al., 201358
|
5, 15 or 30 µM |
24 hours |
To study the link between actin dynamics and Formin activity related to YAP/TAZ activity |
| Yu et al., 201357
|
50 µM |
up to ~49 minutes |
To study the requirement of Formin activity for podosome formation in RPTPalpha++ mouse embryonic fibroblasts |
| Iskratsch et al., 201341
|
5 - 10 µM |
up to 40 minutes |
To confirm the contribution of FHOD1 on cell spreading and adhesion maturation |
| Luo et al., 201344
|
20 - 40 uM |
24 hours |
To study the formation of actin nodes that mediate the formation of actin network within HeLa cells |
| Murk et al., 201346
|
75 µM |
2 hours |
To study the contribution of Formin on transition of stellate astrocytes to polygonal cells during Arp2/3 complex inhibition |
| Buvall et al., 201359
|
10 µM |
90 minutes |
To examine the Formin-dependency of stress fibre formation in podocytes |
| 2014 |
Jennings et al., 201442
|
10 µM |
pretreatment not specified |
To show that priming or degranulation of neutrophil is suppressed by Formins downstream of RhoA |
| Pettee et al., 201448
|
10 µM |
48 hours |
To confirm that organized ovarian spheroid formation of ES-2 cells is dependent on mDia2 |
| Tien and Chang, 201454
|
10 - 100 µM |
4 hours |
To show the correlation between Dia1 inhibition and regulation of ERK activity in MDCK cells |
| Beckham et al., 201461
|
10 µM |
4 hours |
To show the mechanism of formation of lamellipodia in MCF10A cells |
| Harris et al., 201462
|
40 µM |
1 hour |
To assess the mechanism controlling establishment of tissue-level tension in MDCK-II cell monolayers |
| Kajita et al., 201463
|
25 µM |
12-24 hours |
To assess apical extrusion of ts-Src- or RasV12-MDCK cells |
| Lechuga et al., 201464
|
50 µM |
24 hours |
To assess (epithelial to myofibroblast transition) EMyT induction in A549 cells |
