Table 3. Correlation of %HP extent and %WB extent with several factors.

%HP extent
	Single correlation analysis		Multiple linear regression analysis
	r	P	β	P
Log tHcy	0.51	<0.01	0.46	<0.01
BMI	-0.38	0.03	-0.28	0.08
baPWV	0.43	0.01	0.23	0.16
%WB extent
	Single correlation analysis		Multiple linear regression analysis
	r	P	β	P
Age	0.65	<0.01	0.60	<0.01
sAlb	-0.48	<0.01	-0.25	0.11
baPWV	0.61	<0.01	0.14	0.47

%HP extent was related to high log tHcy level. On the other hand, %WB extent was related to high age, significantly.

Abbreviations are; %HP, percentage of hippocampal atrophy; %WB, percentage of whole-brain atrophy; tHcy, total homocysteine; BMI, body mass index; baPWV, brachial-ankle pulse wave velocity; sAlb, serum albumin.