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. 2017 Apr 10;12(4):e0175498. doi: 10.1371/journal.pone.0175498

Fig 1. Irisin promoted the proliferation of pancreatic β cells.

Fig 1

(A) INS-1 cells were cultured and treated with different concentrations of irisin (0, 40, 60, 80, 100 and 150 ng/ml) for 24 h. * P<0.05 compared with the control (0 ng/ml) group; # P<0.05 compared with the 40, 60, 80 ng/ml irisin-treated group; Φ P>0.05 compared with the 100 ng/ml irisin-treated group. (B) INS-1 cells were treated with 100 ng/ml irisin for various time intervals (0, 6, 12, 18, 24, and 48 h). * P<0.05 compared with 0 h; # P<0.05 compared with 6, 12, 18 h; Φ P>0.05 compared with 24 h.