Table 2. Association between lncRNA polymorphisms and platinum-based chemotherapy toxicity.

Type of toxicity	Gene	SNP	Genotype	Grade 0–2 n (%)	Grade 3–4 n (%)	Additive		Dominant		Recessive
						OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Overall toxicity	ANRIL	rs1333049	GG	69 (24.3)	32 (17.8)	0.723 (0.541, 0.965)	0.028*	0.662 (0.424, 1.035)	0.070	0.649 (0.399, 1.054)	0.080
			GC	152 (53.5)	97 (53.9)
			CC	63 (22.2)	51 (28.3)
Gastrointestinal toxicity	ANRIL	rs1333049	GG	83 (22.9)	18 (17.8)	0.690 (0.489, 0.974)	0.035*	0.558 (0.335, 0.931)	0.025*	0.711 (0.396, 1.276)	0.252
			GC	198 (54.5)	51 (50.5)
			CC	82 (22.6)	32 (31.7)
	MEG3	rs116907618	CC	1 (0.3)	2 (1.9)	1.717 (1.007, 2.927)	0.047*	1.678 (0.941, 2.992)	0.080	6.149 (0.540, 70.060)	0.143
			CG	51 (13.9)	20 (19.8)
			GG	314 (85.8)	79 (78.2)

Abbreviations: SNP, single nucleotide polymorphism; n, number; OR, odd ratio; CI, confidence interval.

^*P<0.05.