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. 2017 Jan 5;8(1):e2539. doi: 10.1038/cddis.2016.468

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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High expression of TAZ in OS. TAZ expression was higher in human OS tissues than in chondroma tissues. (A) TAZ staining in OS (e–g) and chondroma tissues (a–c). Magnifications: × 100 (a, e), × 200 (b, f) and × 400 (c, g). Representative results are shown. The areas that were magnified as panels b, c, f and g were marked in panels a, b, e and f, respectively. (d and h) Represent hematoxylin and eosin (H&E) staining of chondroma tissues and OS tissues, respectively. (B) TAZ mRNA expression was higher in human malignant OS tissues than human chondroma-innocent tumor tissues. (C) TAZ protein expression was higher in human OS cell lines than in non-transformed human osteoblastic cells. (D) TAZ mRNA expression was higher in human OS cell lines than in non-transformed human osteoblastic cells (n=4, mean±S.D., *P<0.01)