Figure 2.

Schematic of the CYP4V2 gene showing the position of SNPs and the risk haplotypes. The alleles in various families are shown below the schematic. Families and individuals are grouped by population with Japanese in the top panel, Chinese in the middle panel, and Koreans in the bottom panel. The risk haplotype identified unambiguously in individuals homozygous for the c.802-8_810del17insGC indel mutation is shaded dark blue. The risk haplotype predicted in individuals heterozygous for the c.802-8_810del17insGC indel mutation is shaded light blue. Alleles showing or beyond recombination events and not included in the risk haplotype are not shaded. A full color version of this figure is available at the European Journal of Human Genetics journal online.