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. 2017 Feb 1;25(4):432–438. doi: 10.1038/ejhg.2016.203

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Copyright © 2017 The Author(s)

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Genomic landscape at the region containing the CNV deletion overlapping CYP2A7. The location of the CNV deletion and the enhancer predicted by Hnisz et al²⁸ to affect EGLN2 are shown by black bars. Histone modifications associated with enhancer elements (H3K27Ac and H3K4Me1) and DNAseI hypersensitivity sites (HSs) for normal ovarian tissue and normal breast epithelial cells (HMECs) from Roadmap Epigenomics Consortium and ENCODE are depicted by histogram tracks.