Table 1.
R. | Age (yr), Country of origin, sexual orientation | Time since arrival to US (yr) | Signs and symptoms | Clinical Sd [2] | CD4 count (T cell/µL)/VL (copies/mL) | ART therapy | Eosinophilia (>400 cells/µL) | Steroids | Coinfections/complications | SS Isolation | Initial therapy | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|---|
[4] | 49, Liberia, Unknown | 4 yr | Abdominal pain, pedal edema | HI | 59/Unknown | No | No | No | None | Ascitic fluid, Stool | TBZ (2 w) | Alive |
[8] | 40, Columbia, Unknown | Unknown | Dyspnea, cough, weight loss | HI | Unknown | No | No | Unknown | E. coli meningitis, Klebsiella pneumoniae sepsis | Sputum | TBZ (10 d) | Death |
[5] | 41, Hispanic, Unknown | Unknown | Fever, dyspnea, abdominal pain, vomiting, diarrhea | HI | 31/123,000 | Yes | Yes | No | None | Duodenal biopsy | IVM (14 d) | Alive |
[11] | 60, North America, Homosexual | N/A | Epigastric pain, diarrhea | HI | 194/Unknown | Yes | No | No | None | Duodenal biopsy/BAL | TBZ (3 d) | Death |
[10] | 34, Puerto Rico, Unknown | 15 yr | Pleuritic chest pain, cough, abdominal pain, diarrhea | HI | Unknown | No | Unknown | No | Strep. pneumoniae and Proteus mirabilis sepsis, Proteus mirabilis meningitis | Postmortem | None | Death |
[10] | 40, Puerto Rico, Homosexual | 10 yr | Cough, fever, diarrhea | HI | 34/Unknown | Unknown | Yes | No | Klebsiella pneumoniae sepsis, failure of initial TBZ course | Sputum, Stool | TBZ (≥35 d) | Death |
[10] | 49, Puerto Rico, Unknown | 30 yr | Pleuritic chest pain, cough, fever, weight loss | HI | 36/Unknown | No | Yes | No | Candidemia, pulmonary tuberculosis, ARDS | Sputum, Stool | TBZ (59 d) | Death |
[12] | 28, Unknown, Unknown | Unknown | Dyspnea, Vomiting-abdominal pain, anorexia | HI | Unknown | Unknown | Unknown | Yes | None | Sputum, stool | TBZ (2 w) | Alive |
[13] | 41, Unknown, Unknown | Unknown | Vomiting, anorexia, fever, headache | DS | 50/Unknown | No | Unknown | No | E. coli and Pseudomonas aeruginosa meningitis | Skin biopsy, sputum, nasogastric fluid | TBZ (28 d) IVM (6d) | Death |
[14] | 30, Haiti, Unknown | Unknown | Fever/AMS | HI | 72/Unknown | Unknown | No | No | Streptococcus faecalis meningitis | BAL | TBZ (2 d) | Death |
[15] | 45, Puerto Rico, Unknown | 22 yr | 3rd nerve palsy, urinary retention, Babinski | DS | Unknown | No | Yes | Yes | E. coli bacteremia | CSF | TBZ | Death |
CR | 61, North America, Homosexual | N/A | Abdominal pain, diarrhea. | CS | 235/undetectable | Yes | No | No | No | Colonic biopsy | IVM (10 d) | Alive |
R. – references; yr – year; SS – S. stercoralis; HI – hyperinfection; TBZ – thiobendazole; CR – case report; CS – chronic Strongyloidiasis; IVM – ivermectine; DS – disseminated Strongyloidiasis; BAL – Bronchoalveolar lavage; CSF – Cerebrospinal fluis, AMS – altered mental status; E. coli – Escherichia coli.
Patient received chemotherapy.