Figure 5.

OS of the same p53−/− and p53Q/− animals with T-lymphoma as in Figure 4, with or without weekly treatment with CTX alone (100 mg/kg), ganetespib alone (Gan, 50 mg/kg) or both drugs in combination (100 mg/kg CTX+50 mg/kg Gan). (a) p53−/− animals. (b) p53Q/− animals. (c and d) Paired p53Q/− versus p53−/− analysis of OS of Gan-treated mice (c) and CTX+Gan-treated mice (d) of the indicated genotypes. Kaplan–Meier analysis; n, number of mice; p, log rank statistics. Dots represent censored animals