Table 1. Response of p53 R248Q/− mice bearing autochthonous T-lymphomas to combinatorial treatment with CTX (100 mg/kg) and ganetespib (50 mg/kg).

Mice treated with CTX+Ganet	OS after treatment start, in days	T-lymphoma growth at end point, relative to initial size	Cause of death
Mouse #1a	19	1-fold	Interstitial pneumonia
Mouse #2	19	2.6-fold	T-lymphoma
Mouse #3	26	1.5-fold	Lung atelectasis, T-lymphoma
Mouse #4	62	3.4-fold	T-lymphoma
Mouse #5a	65	0.3-fold	Cause of death unknown. 11 days prior to death thymus still in regression (0.3-fold of original tumor size)
Mouse #6a	121	0.1-fold	Anal obstruction due to fibrosarcoma

^aCensored in PFS and OS curves (Figures 4b and d and Figures 5b and d) since death was not due to T-lymphoma