Figure 1.

Neuronal Atg7 deficiency reduces neural stem and progenitor cell death in the dentate gyrus and cerebellum. (a) Representative hematoxylin and eosin (HE) staining in the dentate gyrus. (b) Quantification of pyknotic cells in the SGZ of the dentate gyrus. (c) Representative HE staining in a cerebellar lobule. (d) Bar graph showing the density of pyknotic cells in the EGL of the cerebellum. (e) Representative active caspase-3 staining in the dentate gyrus. (f) The density of active caspase-3-positive cells in the SGZ of the dentate gyrus. (g) Representative active caspase-3 staining in a cerebellar lobule. (h) The density of active caspase-3-positive cells in the EGL of the cerebellum; n=7 per group. *P<0.05 and ***P<0.001