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. 2017 Mar 30;8(3):e2714. doi: 10.1038/cddis.2017.134

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Copyright © 2017 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Inhibiting miR-491-5p contributes to gastric cell growth and apoptosis. (a) MTT assay of MKN45/SGC-7901 cells after transfection with ASO-miR-491 or a negative control. (b) The growth of MKN45/SGC-7901 cells was detected by colony formation after transfection with ASO-miR-491 or a negative control. (c) Apoptosis was determined in MKN45/SGC-7901 cells transfected with ASO-miR-491 or a negative control. (d) Cell cycle was determined in MKN45/SGC-7901 cells transfected with ASO-miR-491 or a negative control. (e) The expression of pro-caspase 3, active caspase 3, cleaved PARP, BCL-2, CDK2, CCNA2, and β-catenin was analyzed by western blot (*P<0.05, **P<0.01)