Table 1. Clinicopathologic characteristics of patients according to Wnt3a expression.
| Variables | Wnt3a negative (N, %) | Wnt3a positive (N, %) | χ2 | P-value |
|---|---|---|---|---|
| Gender | ||||
| Male | 21 (84.0) | 24 (52.2) | 7.069 | 0.010* |
| Female | 4 (16.0) | 22 (47.8) | ||
| Age (years) | ||||
| Median, range (64, 24–84) | ||||
| <60 | 12 (48.0) | 21 (47.7) | 1.119 | 0.681 |
| ⩾60 | 13 (52.0) | 23 (52.2) | ||
| Location | ||||
| Upper | 9 (36.0) | 11 (25.0) | 2.834 | 0.481 |
| Middle | 1 (4.0) | 5 (11.4) | ||
| Down | 15 (60.0) | 28 (63.6) | ||
| Tumor size (mm) | ||||
| <5 cm | 9 (36.0) | 14 (30.4) | 0.229 | 0.791 |
| ⩾5 cm | 16 (64.0) | 32 (69.6) | ||
| Histologic type | ||||
| Tubular adenocarcinoma | 11 (44.0) | 15 (32.6) | 1.017 | 0.577 |
| Mucinous adenocarcinoma | 8 (32.0) | 15 (32.6) | ||
| Signet-ring cell carcinoma | 6 (24.0) | 16 (34.8) | ||
| T stage | ||||
| T1 | 0 (0) | 2 (6.9) | 6.714 | 0.200 |
| T2 | 1 (5.3) | 2 (6.9) | ||
| T3 | 14 (73.6) | 23 (79.3) | ||
| T4A | 3 (15.8) | 0 (0) | ||
| T4B | 1 (5.3) | 2 (6.9) | ||
| N stage | ||||
| N0 | 6 (26.1) | 9 (22.0) | 1.948 | 0.885 |
| N1 | 3 (13.0) | 9 (22.0) | ||
| N2 | 6 (26.1) | 12 (29.3) | ||
| N3A | 7 (30.4) | 8 (19.5) | ||
| N3B | 1 (4.3) | 3 (7.3) | ||
| Metastasis | ||||
| Negative | 25 (100.0) | 45 (97.8) | 0.551 | 1.000 |
| Positive | 0 (0) | 1 (2.2) | ||
| pTNM stage | ||||
| IA | 0 (0) | 1 (4.2) | 7.337 | 0.496 |
| IB | 1 (5.9) | 0 (0) | ||
| IIA | 4 (23.5) | 5 (20.8) | ||
| IIB | 3 (17.6) | 4 (16.7) | ||
| IIIA | 3 (17.6) | 9 (37.5) | ||
| IIIB | 5 (29.4) | 3 (12.5) | ||
| IIIC | 1 (5.9) | 2 (83.3) | ||
| IV | 0 (0) | 0 (0) | ||
| Regional lymphatic invasion | ||||
| Negative | 6 (25.0) | 13 (28.3) | 0.085 | 0.788 |
| Positive | 18 (75.0) | 33 (71.7) | ||
| Perineural invasion | ||||
| Negative | 25 (100.0) | 37 (80.4) | 5.601 | 0.022* |
| Positive | 0 (0) | 9 (19.6) | ||