Table 1. Standardization of frequencies in NSCLC cells and their genetic background.
Cell line | Standardized TTFields frequency (kHz) | % of growth inhibition at 72 h | P53 status | KRAS status | Doubling time (h) |
---|---|---|---|---|---|
H157 | 100 | 72 | Mutant | Wild type | 36 |
H4006 | 150 | 69 | SNP MS | Wild type | 34 |
A549 | 200 | 48 | Wild type | Mutant | 22 |
H1299 | 100 | 32 | Mutant | Wild type | 20 |
H1650 | 100 | 21 | Wild type | Wild type | 26 |
List of cell lines used and their optimized frequency at which maximal growth inhibition was observed, average percentage of growth inhibition at the optimized frequency after 72 h of TTFields exposure, genetic background information and cell cycle-doubling time (N=3)