Skip to main content
. 2017 Mar 30;8(3):e2720. doi: 10.1038/cddis.2017.137

Figure 6.

Figure 6

Akt/mTOR and Erk signaling pathway played a critical role in rhArg-induced autophagy in H1975 cells. (a) H1975 cells were incubated with different concentrations of rhArg for 24 h, then western blot was performed to analyze the protein p-Akt, p-mTOR, p-P70S6K, p-4EBP1 and p-Erk 1/2. Densitometric values were quantified using the ImageJ software and normalized to control. The values of control were set to 1. The data are presented as means±S.D. of three independent experiments. (b) H1975 cells were incubated with 2 U/ml of rhArg for indicated time, then western blot was performed to analyze the protein p-Akt, p-mTOR, p-P70S6K, p-4EBP1 and p-Erk 1/2. Densitometric values were quantified as described in a